Ferula hermonis research and review
An intriguing study in male rats showed that Ferula hermonis, when given one time, enhanced sexual activity, and also raised blood levels of testosterone. However, when Ferula hermonis was given daily for 10 days, it actually reduced sexual activity, and also reduced testosterone levels. This is difficult to explain but my guess would be that perhaps the dose given to the rats was too high.
Passion Rx for a man and woman - Formulated by
a board certified medical doctor
This male and female enhancement product provides results that are sometimes seen within hours, but continue to improve the next day, and over several days of use. Users of this product notice more libido and sexual thoughts, improved erectile function and genital sensation, and more intense orgasms and climaxes
and herbal expert
Dr. Ray Sahelian, M.D, author of
Natural Sex Boosters, has discovered a
aphrodisiac herbal extracts from the Amazon jungle, India, China, Malaysia, and Africa,
that, when combined, improve issues with
female impotence, as well as
to simply enhance sexual pleasure. Passion Rx provides a
natural option for those looking for an alternative to synthetic medications.
The effective nutrients and herbal extracts in Passion Rx include acetylcarnitine, ashwagandha, catuaba, choline, cnidium monnieri, coleus forskohlii, dmae, epimedium, maca extract, mucuna pruriens, muira puama, passion flower, pfaffia paniculata, rehmannia, rhodiola, shilajit, tribulus terrestris, tongkat ali. Passion Rx does not have Ferula hermonis at this time. Another version of Passion Rx is available with yohimbe, an herb from Africa.
Compounds found in Ferula
Ferula hermonis extract has sesquiterpenes called ferutinin, teferin and teferdin.
Role of ferutinin in the impairment of female
sexual function induced by Ferula hermonis.
Physiol Behav. 2006. Zavatti M, Montanari C, Zanoli P. Department of Biomedical Sciences, Section of Pharmacology, and National InterUniversity Consortium for the Study of Natural Active Principles (CINSPAN), University of Modena and Reggio Emilia, Italy.
In the present study, we evaluated the effects of single components of Ferula hermonis extract on female rat sexual behavior. Ovariectomized rats hormonally primed with estradiol benzoate and progesterone were acutely treated by oral gavage with ferutinin, teferin and teferdin. Thereafter they were tested for: a) partner preference, b) receptivity, c) proceptivity, d) paced mating behavior. In the partner preference test, the choice of the female for a sexually active male was not influenced by the different treatments. Similarly, during the paced mating test, the contact-return latencies as well as the percentage of exits from the male compartment were not different in control and treated rats. Therefore none of the three compounds showed the capacity to alter sexual motivation. On the other hand, ferutinin, but not teferin and teferdin, significantly inhibited female receptivity. These results suggest a primary role of ferutinin in the impairment of sexual behaviour elicited by Ferula hermonis extract in hormone primed-female rats.
Ferula hermonis Research study
Opposite effect of acute and subchronic treatments with Ferula hermonis on copulatory behavior of male rats.
Int J Impot Res. 2003.
Sexually potent and sluggish/impotent male rats were orally treated with an extract of Ferula hermonis (30 and 60 mg/kg). The acute Ferula hermonis administration stimulated sexual motivation in potent rats and improved copulatory performance in sluggish/impotent rats. This last effect was elicited only by the higher Ferula hermonis dose, which, in parallel, increased serum testosterone levels in rats. On the contrary, when the extract was subchronically administered (10 days) a marked reduction in the percentage of rats achieving ejaculation was detected, together with a general impairment of the copulatory pattern. Furthermore, the repeated administration of the Ferula hermonis extract (6 mg/kg/day for 10 days) resulted in a significant reduction of testosterone levels in comparison with controls. The present results discourage a repeated assumption of Ferula hermonis, while suggesting its acute administration to improve the performance in sexual dysfunctions.
Comments: it appears that Ferula hermonis is more suited for short term use and not necessarily appropriate for long term sexual health. One option is to use a Ferula hermonis supplement for a few days and then take a couple of week or more off.
A comparative study of Ferula hermonis root extracts and sildenafil on
copulatory behavior of male rats.
The effect of 600 mg/kg given by oral route to rats of Ferula hermonis roots extracts was evaluated on sexual behavior of male rats. Petroleum ether and ethyl acetate extracts of Ferula hermonis produced a significant decrease in both the mount rate (MR) and the intromission rate (IR), significant prolongation of intromission latency (IL) was observed when these extracts were compared with both controls and sildenafil. Methanolic Ferula hermonis extract produced a significant increase in MR while no effect has been observed on IR or IL in comparison with control. The effect of Ferula hermonis water extract was not significantly different from controls for the MR and IR, but there was a significant prolongation in the IL.