Ferula hermonis herb and sexual enhancement information, combining this herb with other aphrodisiac plants for optimal sexual function

 Zallouh is made from the dried root of the herb Ferula Hermonis which grows at a height of about 2000 meters above sea level on the side of Mount Hermoun between Lebanon and Syria. Ferula hermonis has been used historically in the region as an aphrodisiac, but it has only been in the past few years that scientists have evaluated it's chemical properties. Ferula hermonis contains a number of compounds, including sesquiterpenes. Years ago articles appeared in several magazines that called Ferula hermonis the " Lebanese Viagra."

Ferula hermonis research and review
An intriguing study in male rats showed that Ferula hermonis, when given one time, enhanced sexual activity, and also raised blood levels of testosterone. However, when Ferula hermonis was given daily for 10 days, it actually reduced sexual activity, and also reduced testosterone levels. This is difficult to explain but my guess would be that perhaps the dose given to the rats was too high.

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Ferula hermonis safety
The crude oil from Ferula hermonis can enhance erectile function in rodents, however Ferula hermonis appears to be toxic if used for a long period of time in high doses. In mice, the ingestion of 3 mg/kg of aqueous extract of Ferula hermonis for six weeks inhibited social aggression. Body weight and other sexual accessory organ weights were significantly reduced. The ingestion of high doses of Ferula hermonis by male mice resulted in a reduction of their fertility.
   Sometimes herbs have different effects when given for brief periods as opposed to prolonged periods. Also, the dose of an herb makes a significant difference on how effective it is. Too much can be counterproductive and cause side effects.

Ferula hermonis review
At this point it is difficult to make any firm recommendations regarding the use of Ferula hermonis to enhance libido or to treat erectile dysfunction. Occasional use appears to be safe, but long term use is discouraged until more is known as to the safety of chronic Ferula hermonis ingestion. It is quite possible that the dosages used in rodent studies were quite high compared to what humans would ingest for sexual enhancement purposes.

Compounds found in Ferula hermonis herb
Ferula hermonis extract has sesquiterpenes called ferutinin, teferin and teferdin.

Role of ferutinin in the impairment of female sexual function induced by Ferula hermonis.
Physiol Behav. 2006. Zavatti M, Montanari C, Zanoli P. Department of Biomedical Sciences, Section of Pharmacology, and National InterUniversity Consortium for the Study of Natural Active Principles (CINSPAN), University of Modena and Reggio Emilia, Italy.
In the present study, we evaluated the effects of single components of Ferula hermonis extract on female rat sexual behavior. Ovariectomized rats hormonally primed with estradiol benzoate and progesterone were acutely treated by oral gavage with ferutinin, teferin and teferdin. Thereafter they were tested for: a) partner preference, b) receptivity, c) proceptivity, d) paced mating behavior. In the partner preference test, the choice of the female for a sexually active male was not influenced by the different treatments. Similarly, during the paced mating test, the contact-return latencies as well as the percentage of exits from the male compartment were not different in control and treated rats. Therefore none of the three compounds showed the capacity to alter sexual motivation. On the other hand, ferutinin, but not teferin and teferdin, significantly inhibited female receptivity. These results suggest a primary role of ferutinin in the impairment of sexual behaviour elicited by Ferula hermonis extract in hormone primed-female rats.

Ferula hermonis Research study
Opposite effect of acute and subchronic treatments with Ferula hermonis on copulatory behavior of male rats.
Int J Impot Res. 2003.
Sexually potent and sluggish/impotent male rats were orally treated with an extract of Ferula hermonis (30 and 60 mg/kg). The acute Ferula hermonis administration stimulated sexual motivation in potent rats and improved copulatory performance in sluggish/impotent rats. This last effect was elicited only by the higher Ferula hermonis dose, which, in parallel, increased serum testosterone levels in rats. On the contrary, when the extract was subchronically administered (10 days) a marked reduction in the percentage of rats achieving ejaculation was detected, together with a general impairment of the copulatory pattern. Furthermore, the repeated administration of the Ferula hermonis extract (6 mg/kg/day for 10 days) resulted in a significant reduction of testosterone levels in comparison with controls. The present results discourage a repeated assumption of Ferula hermonis, while suggesting its acute administration to improve the performance in sexual dysfunctions.
     Comments: it appears that Ferula hermonis is more suited for short term use and not necessarily appropriate for long term sexual health. One option is to use a Ferula hermonis supplement for a few days and then take a couple of week or more off.

A comparative study of Ferula hermonis root extracts and sildenafil on copulatory behavior of male rats.
Fitoterapia. 2003.
The effect of 600 mg/kg given by oral route to rats of Ferula hermonis roots extracts was evaluated on sexual behavior of male rats. Petroleum ether and ethyl acetate extracts of Ferula hermonis produced a significant decrease in both the mount rate (MR) and the intromission rate (IR), significant prolongation of intromission latency (IL) was observed when these extracts were compared with both controls and sildenafil. Methanolic Ferula hermonis extract produced a significant increase in MR while no effect has been observed on IR or IL in comparison with control. The effect of Ferula hermonis water extract was not significantly different from controls for the MR and IR, but there was a significant prolongation in the IL.